Meg Whitman resigned as the U.S. Ambassador to Kenya on November 7, 2024. Her resignation came shortly after the victory of Donald Trump in the 2024 presidential election. Whitman cited her pride in leading a “people-centered agenda” during her tenure, focusing on trade, health, and security initiatives that benefited both Kenyans and Americans. Her resignation was also influenced by political dynamics, as her appointment was made by outgoing President Joe Biden, and it is customary for ambassadors to step down when a new president takes office.

Additionally, Whitman faced criticism in Kenya for her perceived close relationship with President William Ruto and allegations of not addressing certain civil rights issues. Despite this, she emphasized the strong and enduring relationship between Kenya and the U.S. and expressed confidence that this partnership would continue to thrive under the new administration​